Timing of Antioxidant Gene Therapy: Implications for Treating Dry AMD

PURPOSE: To investigate whether antioxidant gene therapy protects the structure and function of retina in a murine model of RPE atrophy, and to determine whether antioxidant gene therapy can prevent degeneration once it has begun. METHODS: We induced mitochondrial oxidative stress in RPE by conditio...

Descripción completa

Detalles Bibliográficos
Autores principales: Biswal, Manas R., Han, Pingyang, Zhu, Ping, Wang, Zhaoyang, Li, Hong, Ildefonso, Cristhian J., Lewin, Alfred S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Biochemistry and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338629/
https://www.ncbi.nlm.nih.gov/pubmed/28241311
http://dx.doi.org/10.1167/iovs.16-21272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338629/
https://www.ncbi.nlm.nih.gov/pubmed/28241311
http://dx.doi.org/10.1167/iovs.16-21272

Ejemplares similares