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Timing of Antioxidant Gene Therapy: Implications for Treating Dry AMD

PURPOSE: To investigate whether antioxidant gene therapy protects the structure and function of retina in a murine model of RPE atrophy, and to determine whether antioxidant gene therapy can prevent degeneration once it has begun. METHODS: We induced mitochondrial oxidative stress in RPE by conditio...

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Detalles Bibliográficos
Autores principales:	Biswal, Manas R., Han, Pingyang, Zhu, Ping, Wang, Zhaoyang, Li, Hong, Ildefonso, Cristhian J., Lewin, Alfred S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2017
Materias:	Biochemistry and Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338629/ https://www.ncbi.nlm.nih.gov/pubmed/28241311 http://dx.doi.org/10.1167/iovs.16-21272

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