PDGFRα Is a Key Regulator of T1 and T3's Differential Effect on SMA Expression in Human Corneal Fibroblasts

PURPOSE: The goal of this study was to examine the mechanism behind the unique differential action of transforming growth factor β3 (TGF-β3) and TGF-β1 on SMA expression. It was our hypothesis that platelet-derived growth factor receptor α (PDGFRα) played a key role in determining TGF-β3's resp...

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Detalles Bibliográficos
Autores principales: Sriram, Sriniwas, Tran, Jennifer A., Guo, Xiaoqing, Hutcheon, Audrey E. K., Lei, Hetian, Kazlauskas, Andrius, Zieske, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338631/
https://www.ncbi.nlm.nih.gov/pubmed/28245298
http://dx.doi.org/10.1167/iovs.16-20016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338631/
https://www.ncbi.nlm.nih.gov/pubmed/28245298
http://dx.doi.org/10.1167/iovs.16-20016

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