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Crystallographic analysis of the laminin β2 short arm reveals how the LF domain is inserted into a regular array of LE domains

Laminins are a major constituent of all basement membranes. The polymerisation of laminins at the cell surface is mediated by the three short arms of the cross-shaped laminin heterotrimer. The short arms contain repeats of laminin-type epidermal growth factor-like (LE) domains, interspersed with glo...

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Detalles Bibliográficos
Autores principales: Pulido, David, Briggs, David C., Hua, Jinwen, Hohenester, Erhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338690/
https://www.ncbi.nlm.nih.gov/pubmed/27425256
http://dx.doi.org/10.1016/j.matbio.2016.06.006