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Sample size for detecting differentially expressed genes in microarray experiments

BACKGROUND: Microarray experiments are often performed with a small number of biological replicates, resulting in low statistical power for detecting differentially expressed genes and concomitant high false positive rates. While increasing sample size can increase statistical power and decrease err...

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Detalles Bibliográficos
Autores principales: Wei, Caimiao, Li, Jiangning, Bumgarner, Roger E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC533874/
https://www.ncbi.nlm.nih.gov/pubmed/15533245
http://dx.doi.org/10.1186/1471-2164-5-87