In silico discovery and in vitro activity of inhibitors against Mycobacterium tuberculosis 7,8-diaminopelargonic acid synthase (Mtb BioA)

Computer-aided drug discovery and development approaches such as virtual screening, molecular docking, and in silico drug property calculations have been utilized in this effort to discover new lead compounds against tuberculosis. The enzyme 7,8-diaminopelargonic acid aminotransferase (BioA) in Myco...

Descripción completa

Detalles Bibliográficos
Autores principales: Billones, Junie B, Carrillo, Maria Constancia O, Organo, Voltaire G, Sy, Jamie Bernadette A, Clavio, Nina Abigail B, Macalino, Stephani Joy Y, Emnacen, Inno A, Lee, Alexandra P, Ko, Paul Kenny L, Concepcion, Gisela P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338852/
https://www.ncbi.nlm.nih.gov/pubmed/28280303
http://dx.doi.org/10.2147/DDDT.S119930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338852/
https://www.ncbi.nlm.nih.gov/pubmed/28280303
http://dx.doi.org/10.2147/DDDT.S119930

Ejemplares similares