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Enhancement of pomalidomide anti-tumor response with ACY-241, a selective HDAC6 inhibitor

Thalidomide-based Immunomodulatory Drugs (IMiDs(®)), including lenalidomide and pomalidomide, are effective therapeutics for multiple myeloma. These agents have been approved with, or are under clinical development with, other targeted therapies including proteasome inhibitors, αCD38 monoclonal anti...

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Detalles Bibliográficos
Autores principales: North, Brian J., Almeciga-Pinto, Ingrid, Tamang, David, Yang, Min, Jones, Simon S., Quayle, Steven N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338861/
https://www.ncbi.nlm.nih.gov/pubmed/28264055
http://dx.doi.org/10.1371/journal.pone.0173507