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Identification and validation of regulatory SNPs that modulate transcription factor chromatin binding and gene expression in prostate cancer

Prostate cancer (PCa) is the second most common solid tumor for cancer related deaths in American men. Genome wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) associated with the increased risk of PCa. Because most of the susceptibility SNPs are located in nonco...

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Detalles Bibliográficos
Autores principales: Jin, Hong-Jian, Jung, Segun, DebRoy, Auditi R., Davuluri, Ramana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338917/
https://www.ncbi.nlm.nih.gov/pubmed/27409348
http://dx.doi.org/10.18632/oncotarget.10520