Longitudinal imaging of HIV-1 spread in humanized mice with parallel 3D immunofluorescence and electron tomography

Dissemination of HIV-1 throughout lymphoid tissues leads to systemic virus spread following infection. We combined tissue clearing, 3D-immunofluorescence, and electron tomography (ET) to longitudinally assess early HIV-1 spread in lymphoid tissues in humanized mice. Immunofluorescence revealed peak...

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Detalles Bibliográficos
Autores principales: Kieffer, Collin, Ladinsky, Mark S, Ninh, Allen, Galimidi, Rachel P, Bjorkman, Pamela J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338924/
https://www.ncbi.nlm.nih.gov/pubmed/28198699
http://dx.doi.org/10.7554/eLife.23282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338924/
https://www.ncbi.nlm.nih.gov/pubmed/28198699
http://dx.doi.org/10.7554/eLife.23282

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