Systems-based Analysis of RIG-I-dependent Signaling Identifies KHSRP as an Inhibitor of RIG-I Receptor Activation

Retinoic acid inducible gene-I (RIG-I) receptor recognizes 5′-triphosphorylated RNA and triggers a signaling cascade that results in the induction of type-I IFN-dependent responses. Its precise regulation represents a pivotal balance between antiviral defenses and autoimmunity. To elucidate cellular...

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Detalles Bibliográficos
Autores principales: Soonthornvacharin, Stephen, Rodriguez-Frandsen, Ariel, Zhou, Yingyao, Galvez, Felipe, Huffmaster, Nicholas J., Tripathi, Shashank, Balasubramaniam, Vinod RMT, Inoue, Atsushi, de Castro, Elisa, Moulton, Hong, Stein, David A., Sánchez-Aparicio, María Teresa, De Jesus, Paul D., Nguyen, Quy, König, Renate, Krogan, Nevan J., García-Sastre, Adolfo, Yoh, Sunnie M., Chanda, Sumit K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338947/
https://www.ncbi.nlm.nih.gov/pubmed/28248290
http://dx.doi.org/10.1038/nmicrobiol.2017.22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338947/
https://www.ncbi.nlm.nih.gov/pubmed/28248290
http://dx.doi.org/10.1038/nmicrobiol.2017.22

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