Arenobufagin activates p53 to trigger esophageal squamous cell carcinoma cell apoptosis in vitro and in vivo

Esophageal squamous cell carcinoma (ESCC) is often diagnosed at late incurable stage and lacks effective treatment strategy. Bufadienolides are cardiotonic steroids isolated from the skin and parotid venom glands of the toad Bufo bufo gargarizans Cantor with novel anticancer activity. However, there...

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Detalles Bibliográficos
Autores principales: Lv, Junhong, Lin, Shaohuan, Peng, Panli, Cai, Changqing, Deng, Jianming, Wang, Mingzhi, Li, Xuejun, Lin, Rongsheng, Lin, Yu, Fang, Ailing, Li, Qiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338965/
https://www.ncbi.nlm.nih.gov/pubmed/28280360
http://dx.doi.org/10.2147/OTT.S104767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338965/
https://www.ncbi.nlm.nih.gov/pubmed/28280360
http://dx.doi.org/10.2147/OTT.S104767

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