Effect of a small molecule Lipid II binder on bacterial cell wall stress

We have recently identified small molecule compounds that act as binders of Lipid II, an essential precursor of bacterial cell wall biosynthesis. Lipid II comprised a hydrophilic head group that includes a peptidoglycan subunit composed of N-acetylglucosamine (GlcNAc) and N-acetylmuramic acid (MurNA...

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Detalles Bibliográficos
Autores principales: Malin, Jakob, Shetty, Amol C, Daugherty, Sean C, de Leeuw, Erik PH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338996/
https://www.ncbi.nlm.nih.gov/pubmed/28280373
http://dx.doi.org/10.2147/IDR.S126254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338996/
https://www.ncbi.nlm.nih.gov/pubmed/28280373
http://dx.doi.org/10.2147/IDR.S126254

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