Loss of hypothalamic corticotropin-releasing hormone markedly reduces anxiety behaviors in mice

A long-standing paradigm posits that hypothalamic corticotropin-releasing hormone (CRH) regulates neuroendocrine functions such as adrenal glucocorticoid release, while extra-hypothalamic CRH plays a key role in stressor-triggered behaviors. Here we report that hypothalamus-specific Crh knockout mic...

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Detalles Bibliográficos
Autores principales: Zhang, Rong, Asai, Masato, Mahoney, Carrie E, Joachim, Maria, Shen, Yuan, Gunner, Georgia, Majzoub, Joseph A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339066/
https://www.ncbi.nlm.nih.gov/pubmed/27595593
http://dx.doi.org/10.1038/mp.2016.136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339066/
https://www.ncbi.nlm.nih.gov/pubmed/27595593
http://dx.doi.org/10.1038/mp.2016.136

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