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ComE, an Essential Response Regulator, Negatively Regulates the Expression of the Capsular Polysaccharide Locus and Attenuates the Bacterial Virulence in Streptococcus pneumoniae

The capsular polysaccharide (CPS) of Streptococcus pneumoniae is the main virulence factors required for effective colonization and invasive disease. The capacity to regulate CPS production at the transcriptional level is critical for the survival of S. pneumoniae in different host niches, but littl...

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Detalles Bibliográficos
Autores principales: Zheng, Yuqiang, Zhang, Xuemei, Wang, Xiaofang, Wang, Libin, Zhang, Jinghui, Yin, Yibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339220/
https://www.ncbi.nlm.nih.gov/pubmed/28326061
http://dx.doi.org/10.3389/fmicb.2017.00277