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Estrone Sulfate Transport and Steroid Sulfatase Activity in Colorectal Cancer: Implications for Hormone Replacement Therapy

Hormone replacement therapy (HRT) affects the incidence and potential progression of colorectal cancer (CRC). As HRT primarily consists of estrone sulfate (E(1)S), understanding whether this conjugated estrogen is transported and metabolized in CRC will define its potential effect in this malignancy...

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Detalles Bibliográficos
Autores principales: Gilligan, Lorna C., Gondal, Ali, Tang, Vivien, Hussain, Maryam T., Arvaniti, Anastasia, Hewitt, Anne-Marie, Foster, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339229/
https://www.ncbi.nlm.nih.gov/pubmed/28326039
http://dx.doi.org/10.3389/fphar.2017.00103