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The GABAergic Hypothesis for Cognitive Disabilities in Down Syndrome

Down syndrome (DS) is a genetic disorder caused by the presence of a third copy of chromosome 21. DS affects multiple organs, but it invariably results in altered brain development and diverse degrees of intellectual disability. A large body of evidence has shown that synaptic deficits and memory im...

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Detalles Bibliográficos
Autores principales: Contestabile, Andrea, Magara, Salvatore, Cancedda, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339239/
https://www.ncbi.nlm.nih.gov/pubmed/28326014
http://dx.doi.org/10.3389/fncel.2017.00054