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Neuronal Nitric Oxide Synthase in Neural Stem Cells Induces Neuronal Fate Commitment via the Inhibition of Histone Deacetylase 2

Active adult neurogenesis produces new functional neurons, which replace the lost ones and contribute to brain repair. Promoting neurogenesis may offer a therapeutic strategy for human diseases associated with neurodegeneration. Here, we report that endogenous neuronal nitric oxide synthase (nNOS) f...

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Detalles Bibliográficos
Autores principales: Jin, Xing, Yu, Zhang-Feng, Chen, Fang, Lu, Guang-Xian, Ding, Xin-Yuan, Xie, Lin-Jun, Sun, Jian-Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339248/
https://www.ncbi.nlm.nih.gov/pubmed/28326018
http://dx.doi.org/10.3389/fncel.2017.00066