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Evaluation of Rint1 as a modifier of intestinal tumorigenesis and cancer risk
The Rad50 Interacting Protein 1 (Rint1) influences cellular homeostasis through maintenance of endoplasmic reticulum, Golgi and centrosome integrity and regulation of vesicle transport, autophagy and the G(2)/M checkpoint. Rint1 has been postulated to function as a tumor suppressor as well as an onc...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339343/ https://www.ncbi.nlm.nih.gov/pubmed/28264000 http://dx.doi.org/10.1371/journal.pone.0172247 |