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A role for MALT1 activity in Kaposi's sarcoma-associated herpes virus latency and growth of primary effusion lymphoma

Primary effusion lymphoma (PEL) is an incurable malignancy that develops in immunodeficient patients as a consequence of latent infection of B-cells with Kaposi's sarcoma-associated herpes virus (KSHV). Malignant growth of KSHV-infected B cells requires the activity of the transcription factor...

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Detalles Bibliográficos
Autores principales: Bonsignore, L, Passelli, K, Pelzer, C, Perroud, M, Konrad, A, Thurau, M, Stürzl, M, Dai, L, Trillo-Tinoco, J, Del Valle, L, Qin, Z, Thome, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339436/
https://www.ncbi.nlm.nih.gov/pubmed/27538487
http://dx.doi.org/10.1038/leu.2016.239