IRS-2 Partially Compensates for the Insulin Signal Defects in IRS-1(−/−) Mice Mediated by miR-33

Insulin signaling is coordinated by insulin receptor substrates (IRSs). Many insulin responses, especially for blood glucose metabolism, are mediated primarily through Irs-1 and Irs-2. Irs-1 knockout mice show growth retardation and insulin signaling defects, which can be compensated by other IRSs i...

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Detalles Bibliográficos
Autores principales: Tang, Chen-Yi, Man, Xiao-Fei, Guo, Yue, Tang, Hao-Neng, Tang, Jun, Zhou, Ci-La, Tan, Shu-Wen, Wang, Min, Zhou, Hou-De
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339503/
https://www.ncbi.nlm.nih.gov/pubmed/28190325
http://dx.doi.org/10.14348/molcells.2017.2228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339503/
https://www.ncbi.nlm.nih.gov/pubmed/28190325
http://dx.doi.org/10.14348/molcells.2017.2228

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