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IRS-2 Partially Compensates for the Insulin Signal Defects in IRS-1(−/−) Mice Mediated by miR-33
Insulin signaling is coordinated by insulin receptor substrates (IRSs). Many insulin responses, especially for blood glucose metabolism, are mediated primarily through Irs-1 and Irs-2. Irs-1 knockout mice show growth retardation and insulin signaling defects, which can be compensated by other IRSs i...
Autores principales: | Tang, Chen-Yi, Man, Xiao-Fei, Guo, Yue, Tang, Hao-Neng, Tang, Jun, Zhou, Ci-La, Tan, Shu-Wen, Wang, Min, Zhou, Hou-De |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Molecular and Cellular Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339503/ https://www.ncbi.nlm.nih.gov/pubmed/28190325 http://dx.doi.org/10.14348/molcells.2017.2228 |
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