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Regulation of Na(+) channel inactivation by the DIII and DIV voltage-sensing domains
Functional eukaryotic voltage-gated Na(+) (Na(V)) channels comprise four domains (DI–DIV), each containing six membrane-spanning segments (S1–S6). Voltage sensing is accomplished by the first four membrane-spanning segments (S1–S4), which together form a voltage-sensing domain (VSD). A critical Na(V...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339511/ https://www.ncbi.nlm.nih.gov/pubmed/28232510 http://dx.doi.org/10.1085/jgp.201611678 |