Cargando…

Regulation of Na(+) channel inactivation by the DIII and DIV voltage-sensing domains

Functional eukaryotic voltage-gated Na(+) (Na(V)) channels comprise four domains (DI–DIV), each containing six membrane-spanning segments (S1–S6). Voltage sensing is accomplished by the first four membrane-spanning segments (S1–S4), which together form a voltage-sensing domain (VSD). A critical Na(V...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hsu, Eric J., Zhu, Wandi, Schubert, Angela R., Voelker, Taylor, Varga, Zoltan, Silva, Jonathan R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339511/ https://www.ncbi.nlm.nih.gov/pubmed/28232510 http://dx.doi.org/10.1085/jgp.201611678

Ejemplares similares

Conformations of voltage-sensing domain III differentially define Na(V) channel closed- and open-state inactivation
por: Angsutararux, Paweorn, et al.
Publicado: (2021)

Mechanisms of noncovalent β subunit regulation of Na(V) channel gating
por: Zhu, Wandi, et al.
Publicado: (2017)

Interactions among DIV voltage-sensor movement, fast inactivation, and resurgent Na current induced by the Na(V)β4 open-channel blocking peptide
por: Lewis, Amanda H., et al.
Publicado: (2013)

Physics of electron cyclotron current drive on DIII-D
por: Petty, C C, et al.
Publicado: (2002)

Mutations at opposite ends of the DIII/S4-S5 linker of sodium channel Na(V)1.7 produce distinct pain disorders
por: Cheng, Xiaoyang, et al.
Publicado: (2010)

A Mechanistic Reinterpretation of Fast Inactivation in Voltage-Gated Na(+) Channels
por: Liu, Yichen, et al.
Publicado: (2023)

A mechanistic reinterpretation of fast inactivation in voltage-gated Na(+) channels
por: Liu, Yichen, et al.
Publicado: (2023)

A Mechanistic Reinterpretation of Fast Inactivation in Voltage-Gated Na(+) Channels
por: Liu, Yichen, et al.
Publicado: (2023)

Slow Inactivation Does Not Affect Movement of the Fast Inactivation Gate in Voltage-gated Na(+) Channels
por: Vedantham, Vasanth, et al.
Publicado: (1998)

Depolarization of the conductance-voltage relationship in the Na(V)1.5 mutant, E1784K, is due to altered fast inactivation
por: Peters, Colin H., et al.
Publicado: (2017)

The Position of the Fast-Inactivation Gate during Lidocaine Block of Voltage-gated Na(+) Channels
por: Vedantham, Vasanth, et al.
Publicado: (1999)

Propofol inhibits prokaryotic voltage-gated Na(+) channels by promoting activation-coupled inactivation
por: Yang, Elaine, et al.
Publicado: (2018)

The isolated voltage sensing domain of the Shaker potassium channel forms a voltage-gated cation channel
por: Zhao, Juan, et al.
Publicado: (2016)

Molecular Pathology of Sodium Channel Beta-Subunit Variants
por: Angsutararux, Paweorn, et al.
Publicado: (2021)

A Novel Spider Toxin Inhibits Fast Inactivation of the Na(v)1.9 Channel by Binding to Domain III and Domain IV Voltage Sensors
por: Peng, Shuijiao, et al.
Publicado: (2021)

Calcium-driven regulation of voltage-sensing domains in BK channels
por: Lorenzo-Ceballos, Yenisleidy, et al.
Publicado: (2019)

Distinct modulation of inactivation by a residue in the pore domain of voltage-gated Na(+) channels: mechanistic insights from recent crystal structures
por: Cervenka, Rene, et al.
Publicado: (2018)

Observation of suprathermal electrons during magnetic reconnection at the sawtooth instability in DIII-D TOKAMAK
por: Savrukhin, R V, et al.
Publicado: (2002)

Slow Inactivation Does Not Block the Aqueous Accessibility to the Outer Pore of Voltage-gated Na Channels
por: Struyk, Arie F., et al.
Publicado: (2002)

A Voltage Dependent Non-Inactivating Na(+) Channel Activated during Apoptosis in Xenopus Oocytes
por: Englund, Ulrika H., et al.
Publicado: (2014)

Voltage Sensor Inactivation in Potassium Channels
por: Bähring, Robert, et al.
Publicado: (2012)

Role of the voltage sensor module in Na(v) domain IV on fast inactivation in sodium channelopathies: The implication of closed-state inactivation
por: Nakajima, Tadashi, et al.
Publicado: (2019)

Voltage-sensor movements describe slow inactivation of voltage-gated sodium channels I: Wild-type skeletal muscle Na(V)1.4
por: Silva, Jonathan R., et al.
Publicado: (2013)

The Eag Domain Regulates the Voltage-Dependent Inactivation of Rat Eag1 K(+) Channels
por: Lin, Ting-Feng, et al.
Publicado: (2014)

Voltage-gated Na Channel Selectivity: The Role of the Conserved Domain III Lysine Residue
por: Lipkind, Gregory M., et al.
Publicado: (2008)

The intramembrane COOH-terminal domain of PRRT2 regulates voltage-dependent Na(+) channels
por: Franchi, Francesca, et al.
Publicado: (2023)

Caution Is Required in Interpretation of Mutations in the Voltage Sensing Domain of Voltage Gated Channels as Evidence for Gating Mechanisms
por: Kariev, Alisher M., et al.
Publicado: (2015)

Cell-Free Expression of Sodium Channel Domains for Pharmacology Studies. Noncanonical Spider Toxin Binding Site in the Second Voltage-Sensing Domain of Human Na(v)1.4 Channel
por: Myshkin, Mikhail Yu., et al.
Publicado: (2019)

Lacosamide Inhibition of Na(V)1.7 Channels Depends on its Interaction With the Voltage Sensor Domain and the Channel Pore
por: Labau, Julie I. R., et al.
Publicado: (2021)

The voltage-sensing domain of a phosphatase gates the pore of a potassium channel
por: Arrigoni, Cristina, et al.
Publicado: (2013)

Voltage Dependence of Slow Inactivation in Shaker Potassium Channels Results from Changes in Relative K(+) and Na(+) Permeabilities
por: Starkus, John G., et al.
Publicado: (2000)

Rapid voltage-dependent dissociation of scorpion alpha-toxins coupled to Na channel inactivation in amphibian myelinated nerves
Publicado: (1986)

Domain-to-domain coupling in voltage-sensing phosphatase
por: Sakata, Souhei, et al.
Publicado: (2017)

Built for speed: Molecular properties of the voltage sensor domain underlie the rapid activation of voltage-gated Na(+) channels compared with Shaker-type K(+) channels
por: Braun, Andrew P
Publicado: (2013)

Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening
por: Hou, Panpan, et al.
Publicado: (2017)

A mycobacterial DivIVA domain-containing protein involved in cell length and septation
por: Pickford, Hayleah, et al.
Publicado: (2020)

Zeeman-Field-Tuned Topological Phase Transitions in a Two-Dimensional Class-DIII Superconductor
por: Deng, W. Y., et al.
Publicado: (2016)

Josephson effects in the junction formed by DIII-class topological and s-wave superconductors with an embedded quantum dot
por: Gao, Zhen, et al.
Publicado: (2016)

Mechanisms Responsible for ω-Pore Currents in Ca(v) Calcium Channel Voltage-Sensing Domains
por: Monteleone, Stefania, et al.
Publicado: (2017)

Molecular mechanism of voltage sensing in voltage-gated proton channels
por: Gonzalez, Carlos, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_n6o4ugqkpio2g6vs7arum8beko