The Smac Mimetic BV6 Improves NK Cell-Mediated Killing of Rhabdomyosarcoma Cells by Simultaneously Targeting Tumor and Effector Cells

Rhabdomyosarcoma (RMS), the most common cancer of connective tissues in pediatrics, is often resistant to conventional therapies. One underlying mechanism of this resistance is the overexpression of Inhibitor of Apoptosis (IAP) proteins, leading to a dysfunctional cell death program within tumor cel...

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Detalles Bibliográficos
Autores principales: Fischer, Kyra, Tognarelli, Sara, Roesler, Stefanie, Boedicker, Cathinka, Schubert, Ralf, Steinle, Alexander, Klingebiel, Thomas, Bader, Peter, Fulda, Simone, Ullrich, Evelyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339542/
https://www.ncbi.nlm.nih.gov/pubmed/28326081
http://dx.doi.org/10.3389/fimmu.2017.00202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339542/
https://www.ncbi.nlm.nih.gov/pubmed/28326081
http://dx.doi.org/10.3389/fimmu.2017.00202

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