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Up-regulation of TLR2 and TLR4 in high mobility group Box1-stimulated macrophages in pulpitis patients

OBJECTIVE(S): High Mobility Group Box1 (HMGB1) is a nonhistone, DNA-binding protein that serves a crucial role in regulating gene transcription and is involved in a variety of proinflammatory, extracellular activities. The aim of this study was to explore whether HMGB1 stimulation can up-regulate th...

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Detalles Bibliográficos
Autores principales: Mahmoudi, Javad, Sabermarouf, Babak, Baradaran, Behzad, Sadat-Hatamnezhad, Leila, Shotorbani, Siamak Sandoghchian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339663/
https://www.ncbi.nlm.nih.gov/pubmed/28293399
http://dx.doi.org/10.22038/ijbms.2017.8250