Skap2 is required for β(2) integrin–mediated neutrophil recruitment and functions

Integrin activation is required for neutrophil functions. Impaired integrin activation on neutrophils is the hallmark of leukocyte adhesion deficiency (LAD) syndrome in humans, characterized by impaired leukocyte recruitment and recurrent infections. The Src kinase–associated phosphoprotein 2 (Skap2...

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Detalles Bibliográficos
Autores principales: Boras, Mark, Volmering, Stephanie, Bokemeyer, Arne, Rossaint, Jan, Block, Helena, Bardel, Bernadette, Van Marck, Veerle, Heitplatz, Barbara, Kliche, Stefanie, Reinhold, Annegret, Lowell, Clifford, Zarbock, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339670/
https://www.ncbi.nlm.nih.gov/pubmed/28183734
http://dx.doi.org/10.1084/jem.20160647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339670/
https://www.ncbi.nlm.nih.gov/pubmed/28183734
http://dx.doi.org/10.1084/jem.20160647

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