Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer

Pancreatic stellate cells (PSCs) differentiate into cancer-associated fibroblasts (CAFs) that produce desmoplastic stroma, thereby modulating disease progression and therapeutic response in pancreatic ductal adenocarcinoma (PDA). However, it is unknown whether CAFs uniformly carry out these tasks or...

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Detalles Bibliográficos
Autores principales: Öhlund, Daniel, Handly-Santana, Abram, Biffi, Giulia, Elyada, Ela, Almeida, Ana S., Ponz-Sarvise, Mariano, Corbo, Vincenzo, Oni, Tobiloba E., Hearn, Stephen A., Lee, Eun Jung, Chio, Iok In Christine, Hwang, Chang-Il, Tiriac, Hervé, Baker, Lindsey A., Engle, Dannielle D., Feig, Christine, Kultti, Anne, Egeblad, Mikala, Fearon, Douglas T., Crawford, James M., Clevers, Hans, Park, Youngkyu, Tuveson, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339682/
https://www.ncbi.nlm.nih.gov/pubmed/28232471
http://dx.doi.org/10.1084/jem.20162024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339682/
https://www.ncbi.nlm.nih.gov/pubmed/28232471
http://dx.doi.org/10.1084/jem.20162024

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