OGG1-DNA interactions facilitate NF-κB binding to DNA targets

DNA repair protein counteracting oxidative promoter lesions may modulate gene expression. Oxidative DNA bases modified by reactive oxygen species (ROS), primarily as 7, 8-dihydro-8-oxo-2′-deoxyguanosine (8-oxoG), which is repaired by 8-oxoguanine DNA glycosylase1 (OGG1) during base excision repair (...

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Detalles Bibliográficos
Autores principales: Pan, Lang, Hao, Wenjing, Zheng, Xu, Zeng, Xianlu, Ahmed Abbasi, Adeel, Boldogh, Istvan, Ba, Xueqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339705/
https://www.ncbi.nlm.nih.gov/pubmed/28266569
http://dx.doi.org/10.1038/srep43297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339705/
https://www.ncbi.nlm.nih.gov/pubmed/28266569
http://dx.doi.org/10.1038/srep43297

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