Cargando…
OGG1-DNA interactions facilitate NF-κB binding to DNA targets
DNA repair protein counteracting oxidative promoter lesions may modulate gene expression. Oxidative DNA bases modified by reactive oxygen species (ROS), primarily as 7, 8-dihydro-8-oxo-2′-deoxyguanosine (8-oxoG), which is repaired by 8-oxoguanine DNA glycosylase1 (OGG1) during base excision repair (...
Autores principales: | Pan, Lang, Hao, Wenjing, Zheng, Xu, Zeng, Xianlu, Ahmed Abbasi, Adeel, Boldogh, Istvan, Ba, Xueqing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339705/ https://www.ncbi.nlm.nih.gov/pubmed/28266569 http://dx.doi.org/10.1038/srep43297 |
Ejemplares similares
-
Enzymatically inactive OGG1 binds to DNA and steers base excision repair toward gene transcription
por: Hao, Wenjing, et al.
Publicado: (2020) -
The roles of base excision repair enzyme OGG1 in gene expression
por: Wang, Ruoxi, et al.
Publicado: (2018) -
Innate Immune Responses to RSV Infection Facilitated by OGG1, an Enzyme Repairing Oxidatively Modified DNA Base Lesions
por: Zheng, Xu, et al.
Publicado: (2022) -
Substrate-specific binding of 8-oxoguanine DNA glycosylase 1 (OGG1) reprograms mucosal adaptations to chronic airway injury
por: Pan, Lang, et al.
Publicado: (2023) -
OGG1-initiated base excision repair exacerbates oxidative stress-induced parthanatos
por: Wang, Ruoxi, et al.
Publicado: (2018)