Cordycepin disrupts leukemia association with mesenchymal stromal cells and eliminates leukemia stem cell activity

Maintaining stemness of leukemic stem cells (LSCs) and reciprocal interactions between leukemia and stromal cells support leukemic progression and resistance to chemotherapy. Targeting the niche-based microenvironment is thus a new approach for leukemia therapy. Cordycepin is an analogue of adenosin...

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Detalles Bibliográficos
Autores principales: Liang, Shu-Man, Lu, Yi-Jhu, Ko, Bor-Sheng, Jan, Yee-Jee, Shyue, Song-Kun, Yet, Shaw-Fang, Liou, Jun-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339716/
https://www.ncbi.nlm.nih.gov/pubmed/28266575
http://dx.doi.org/10.1038/srep43930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339716/
https://www.ncbi.nlm.nih.gov/pubmed/28266575
http://dx.doi.org/10.1038/srep43930

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