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The trisaccharide raffinose modulates epidermal differentiation through activation of liver X receptor

The epidermal barrier function requires optimal keratinocyte differentiation and epidermal lipid synthesis. Liver X receptor (LXR) α and β, are important transcriptional regulators of the epidermal gene expression. Here, we show that raffinose, a ubiquitously present trisaccharide in plants, activat...

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Detalles Bibliográficos
Autores principales: Na, Tae-Young, Kim, Gyeong-Hwan, Oh, Hyeon-Jeong, Lee, Min-Ho, Han, Yong-Hyun, Kim, Ki Taek, Kim, Ji-Su, Kim, Dae-Duk, Lee, Mi-Ock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339792/
https://www.ncbi.nlm.nih.gov/pubmed/28266648
http://dx.doi.org/10.1038/srep43823