Absence of PD-L1 on tumor cells is associated with reduced MHC I expression and PD-L1 expression increases in recurrent serous ovarian cancer

Immune-evasion and immune checkpoints are promising new therapeutic targets for several cancer entities. In ovarian cancer, the clinical role of programmed cell death receptor ligand 1 (PD-L1) expression as mechanism to escape immune recognition has not been clarified yet. We analyzed PD-L1 expressi...

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Detalles Bibliográficos
Autores principales: Aust, Stefanie, Felix, Sophie, Auer, Katharina, Bachmayr-Heyda, Anna, Kenner, Lukas, Dekan, Sabine, Meier, Samuel M., Gerner, Christopher, Grimm, Christoph, Pils, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339797/
https://www.ncbi.nlm.nih.gov/pubmed/28266500
http://dx.doi.org/10.1038/srep42929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339797/
https://www.ncbi.nlm.nih.gov/pubmed/28266500
http://dx.doi.org/10.1038/srep42929

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