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Nkx2.1 regulates the generation of telencephalic astrocytes during embryonic development

The homeodomain transcription factor Nkx2.1 (NK2 homeobox 1) controls cell differentiation of telencephalic GABAergic interneurons and oligodendrocytes. Here we show that Nkx2.1 also regulates astrogliogenesis of the telencephalon from embryonic day (E) 14.5 to E16.5. Moreover we identify the differ...

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Detalles Bibliográficos
Autores principales: Minocha, Shilpi, Valloton, Delphine, Arsenijevic, Yvan, Cardinaux, Jean-René, Guidi, Raffaella, Hornung, Jean-Pierre, Lebrand, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339799/
https://www.ncbi.nlm.nih.gov/pubmed/28266561
http://dx.doi.org/10.1038/srep43093