A missense mutation in zbtb17 blocks the earliest steps of T cell differentiation in zebrafish

T cells are an evolutionarily conserved feature of the adaptive immune systems of vertebrates. Comparative studies using evolutionarily distant species hold great promise for unraveling the genetic landscape underlying this process. To this end, we used ENU mutagenesis to generate mutant zebrafish w...

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Detalles Bibliográficos
Autores principales: Lawir, Divine-Fondzenyuy, Iwanami, Norimasa, Schorpp, Michael, Boehm, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339814/
https://www.ncbi.nlm.nih.gov/pubmed/28266617
http://dx.doi.org/10.1038/srep44145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339814/
https://www.ncbi.nlm.nih.gov/pubmed/28266617
http://dx.doi.org/10.1038/srep44145

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