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High glucose alters tendon homeostasis through downregulation of the AMPK/Egr1 pathway

Diabetes mellitus (DM) is associated with higher risk of tendinopathy, which reduces tolerance to exercise and functional activities and affects lifestyle and glycemic control. Expression of tendon-related genes and matrix metabolism in tenocytes are essential for maintaining physiological functions...

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Detalles Bibliográficos
Autores principales: Wu, Yu-Fu, Wang, Hsing-Kuo, Chang, Hong-Wei, Sun, Jingyu, Sun, Jui-Sheng, Chao, Yuan-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339827/
https://www.ncbi.nlm.nih.gov/pubmed/28266660
http://dx.doi.org/10.1038/srep44199