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Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis

The persistence of cholesterol-engorged macrophages (foam cells) in the artery wall fuels the development of atherosclerosis. However, the mechanism that regulates the formation of macrophage foam cells and impedes their emigration out of inflamed plaques is still elusive. Here, we report that adhes...

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Detalles Bibliográficos
Autores principales: Luo, Yongting, Duan, Hongxia, Qian, Yining, Feng, Liqun, Wu, Zhenzhen, Wang, Fei, Feng, Jing, Yang, Dongling, Qin, Zhihai, Yan, Xiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339843/
https://www.ncbi.nlm.nih.gov/pubmed/28084332
http://dx.doi.org/10.1038/cr.2017.8