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Preclinical evaluation of multi antigenic HCV DNA vaccine for the prevention of Hepatitis C virus infection

Direct-acting antiviral treatment for hepatitis C virus (HCV) infection is costly and does not protect from re-infection. For human and chimpanzees, recovery from acute HCV infection correlates with host CD4+ and CD8+ T cell responses. DNA plasmids targeting the HCV non-structural antigens NS3, NS4,...

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Detalles Bibliográficos
Autores principales: Lee, Hyojin, Jeong, Moonsup, Oh, Jooyeon, Cho, Youngran, Shen, Xuefei, Stone, John, Yan, Jian, Rothkopf, Zachary, Khan, Amir S., Cho, Byung Mun, Park, Young K., Weiner, David B., Son, Woo-Chan, Maslow, Joel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339862/
https://www.ncbi.nlm.nih.gov/pubmed/28266565
http://dx.doi.org/10.1038/srep43531