Cargando…

Preclinical evaluation of multi antigenic HCV DNA vaccine for the prevention of Hepatitis C virus infection

Direct-acting antiviral treatment for hepatitis C virus (HCV) infection is costly and does not protect from re-infection. For human and chimpanzees, recovery from acute HCV infection correlates with host CD4+ and CD8+ T cell responses. DNA plasmids targeting the HCV non-structural antigens NS3, NS4,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Hyojin, Jeong, Moonsup, Oh, Jooyeon, Cho, Youngran, Shen, Xuefei, Stone, John, Yan, Jian, Rothkopf, Zachary, Khan, Amir S., Cho, Byung Mun, Park, Young K., Weiner, David B., Son, Woo-Chan, Maslow, Joel N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339862/ https://www.ncbi.nlm.nih.gov/pubmed/28266565 http://dx.doi.org/10.1038/srep43531

Ejemplares similares

Severe fever and thrombocytopenia syndrome virus infection: Considerations for vaccine evaluation of a rare disease
por: Maslow, Joel N., et al.
Publicado: (2019)

Herpes Zoster DNA Vaccines with IL-7 and IL-33 Molecular Adjuvants Elicit Protective T Cell Immunity
por: Kim, A Reum, et al.
Publicado: (2018)

Preexisting vs. de novo antibodies against SARS-CoV-2 in individuals without or with virus infection: impact on antibody therapy, vaccine research and serological testing
por: Muthumani, Kar, et al.
Publicado: (2021)

The correlation of HCV RNA and HCV core antigen in different genotypes of HCV
por: Xiang, Yu, et al.
Publicado: (2018)

Hepatitis C virus (HCV) genotypes and the influence of HCV subtype 1b on the progression of chronic hepatitis C in Korea: a single center experience
por: Cho, Eun Ju, et al.
Publicado: (2012)

HCV core antigen and HCV-RNA in HIV/HCV co-infected patients with different HCV genotypes
por: Garbuglia, Anna Rosa, et al.
Publicado: (2014)

Preclinical safety assessment of the suction-assisted intradermal injection of the SARS-CoV-2 DNA vaccine candidate pGO-1002 in white rabbit
por: Oh, Seunghee, et al.
Publicado: (2023)

Effectiveness of HCV core antigen and RNA quantification in HCV-infected and HCV/HIV-1-coinfected patients
por: Long, Lu, et al.
Publicado: (2014)

HCV core antigen plays an important role in the fight against HCV as an alternative to HCV‐RNA detection
por: Wang, Yuhan, et al.
Publicado: (2021)

Development of a SFTSV DNA vaccine that confers complete protection against lethal infection in ferrets
por: Kwak, Jeong-Eun, et al.
Publicado: (2019)

Is HCV core antigen a reliable marker of viral load? An evaluation of HCV core antigen automated immunoassay
por: Hadziyannis, Emilia, et al.
Publicado: (2013)

Hepatitis C diagnosics: clinical evaluation of the HCV-core antigen determination
por: van Helden, Josef
Publicado: (2014)

HCV antigen instead of RNA testing to diagnose acute HCV in patients treated in the Dutch Acute HCV in HIV Study
por: Hullegie, Sebastiaan J., et al.
Publicado: (2017)

The study of hepatitis B surface antigen and anti-HCV in HIV infected patients
por: Girish, N, et al.
Publicado: (2012)

The Relationship between Virological Characteristics of Hepatitis C Virus (HCV) and Reactivity to the Regional Specific Proteins of HCV(*)
por: Yoon, Seung Kew, et al.
Publicado: (2000)

Performance of Hepatitis C Virus (HCV) Core Antigen Assay in the Diagnosis of Recently Acquired HCV Infection among High-Risk Populations
por: Sun, Hsin-Yun, et al.
Publicado: (2022)

An amino acid substitution in HCV core antigen limits its use as a reliable measure of HCV infection compared with HCV RNA
por: Hansoongnern, Payuda, et al.
Publicado: (2023)

Comparison of Quasispecies Diversity of HCV between Chronic Hepatitis C and Hepatocellular Carcinoma by Ultradeep Pyrosequencing
por: Park, Chang-Wook, et al.
Publicado: (2014)

Relationship Between Alcohol Consumption and Risky Sexual Behaviors Among Adolescents and Young Adults: A Meta-Analysis
por: Cho, Hyang-Soon, et al.
Publicado: (2023)

A Higher Correlation of HCV Core Antigen with CD4+ T Cell Counts Compared with HCV RNA in HCV/HIV-1 Coinfected Patients
por: Shen, Tao, et al.
Publicado: (2011)

HCV core antigen is an alternative marker to HCV RNA for evaluating active HCV infection: implications for improved diagnostic option in an era of affordable DAAs
por: Wasitthankasem, Rujipat, et al.
Publicado: (2017)

Interferon Alpha Therapy in Patients with Chronic Type C Hepatitis: Changes of Serum ALT, Anti-HCV & HCV-RNA
por: Cho, Ho Jun, et al.
Publicado: (1992)

Heterologous Immunity between Adenoviruses and Hepatitis C Virus (HCV): Recombinant Adenovirus Vaccine Vectors Containing Antigens from Unrelated Pathogens Induce Cross-Reactive Immunity Against HCV Antigens
por: Agrawal, Babita, et al.
Publicado: (2019)

Hepatitis C virus (HCV) Infection Rate among Seronegative Hemodialysis Patients Screened by Two Methods; HCV Core Antigen and Polymerase Chain Reaction
por: Moini, Maryam, et al.
Publicado: (2013)

Soluble egg antigen of Schistosoma Haematobium induces HCV replication in PBMC from patients with chronic HCV infection
por: El-Awady, Mostafa K, et al.
Publicado: (2006)

Expression of core antigen of HCV genotype 3a and its evaluation as screening agent for HCV infection in Pakistan
por: Yousaf, Muhammad Z, et al.
Publicado: (2011)

Rapid response to an emerging infectious disease – Lessons learned from development of a synthetic DNA vaccine targeting Zika virus
por: Kudchodkar, Sagar B., et al.
Publicado: (2018)

Circulating viral core and E1 antigen levels as supplemental markers for HCV Chronic hepatitis
por: El Awady, Mostafa K, et al.
Publicado: (2006)

Developments in the HCV Screening Technologies Based on the Detection of Antigens and Antibodies
por: Warkad, Shrikant Dashrath, et al.
Publicado: (2019)

Clearance of HCV by Combination Therapy of Pegylated Interferon α-2a and Ribavirin Improves Insulin Resistance
por: Kim, Hong Joo, et al.
Publicado: (2009)

Preclinical safety evaluation of hepatic arterial infusion of oncolytic poxvirus
por: Cho, Euna, et al.
Publicado: (2018)

Evaluation of screening effectiveness of hepatitis B surface antigen and anti-HCV rapid test kits in Pakistan
por: Waheed, Usman, et al.
Publicado: (2019)

Hepatitis C (HCV) therapy for HCV mono-infected and HIV-HCV co-infected individuals living in Nepal
por: KC, Sudhamshu, et al.
Publicado: (2020)

Inactivated Orf Virus Shows Antifibrotic Activity and Inhibits Human Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) Replication in Preclinical Models
por: Paulsen, Daniela, et al.
Publicado: (2013)

GeneOne Life Science
por: Maslow, Joel
Publicado: (2018)

Amino acid sequence homologies between HCV polyprotein and thyroid antigens
por: Martocchia, A., et al.
Publicado: (2007)

Influence of HIV and HCV on T cell antigen presentation and challenges in the development of vaccines
por: John, Mina, et al.
Publicado: (2014)

Hepatitis C virus (HCV) infection and re-infection among HCV- and HIV/HCV-infected injection drug users
por: Conway, B, et al.
Publicado: (2010)

Hepatitis C core antigen test as an alternative for diagnosing HCV infection: mathematical model and cost-effectiveness analysis
por: Sadeghimehr, Maryam, et al.
Publicado: (2021)

Vaccines for emerging infectious diseases: Lessons from MERS coronavirus and Zika virus
por: Maslow, Joel N.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ncsqfok7ir6e02tsuu48sjr3tk