Selective induction of alternatively spliced FynT isoform by TNF facilitates persistent inflammatory responses in astrocytes

Fyn tyrosine kinase has been implicated in the pathogenesis of Alzheimer’s disease (AD). We have previously reported that upregulation of the FynT isoform in AD brains was partly associated with astrocyte activation. In this study, we demonstrated selective FynT induction in murine cortex and primar...

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Detalles Bibliográficos
Autores principales: Lee, Chingli, Low, Clara Y. B., Wong, Siew Ying, Lai, Mitchell K. P., Tan, Michelle G. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339870/
https://www.ncbi.nlm.nih.gov/pubmed/28266558
http://dx.doi.org/10.1038/srep43651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339870/
https://www.ncbi.nlm.nih.gov/pubmed/28266558
http://dx.doi.org/10.1038/srep43651

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