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Selective induction of alternatively spliced FynT isoform by TNF facilitates persistent inflammatory responses in astrocytes
Fyn tyrosine kinase has been implicated in the pathogenesis of Alzheimer’s disease (AD). We have previously reported that upregulation of the FynT isoform in AD brains was partly associated with astrocyte activation. In this study, we demonstrated selective FynT induction in murine cortex and primar...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339870/ https://www.ncbi.nlm.nih.gov/pubmed/28266558 http://dx.doi.org/10.1038/srep43651 |