A proteomic approach to identify endosomal cargoes controlling cancer invasiveness

We have previously shown that Rab17, a small GTPase associated with epithelial polarity, is specifically suppressed by ERK2 (also known as MAPK1) signalling to promote an invasive phenotype. However, the mechanisms through which Rab17 loss permits invasiveness, and the endosomal cargoes that are res...

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Detalles Bibliográficos
Autores principales: Diaz-Vera, Jesica, Palmer, Sarah, Hernandez-Fernaud, Juan Ramon, Dornier, Emmanuel, Mitchell, Louise E., Macpherson, Iain, Edwards, Joanne, Zanivan, Sara, Norman, Jim C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339883/
https://www.ncbi.nlm.nih.gov/pubmed/28062852
http://dx.doi.org/10.1242/jcs.190835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339883/
https://www.ncbi.nlm.nih.gov/pubmed/28062852
http://dx.doi.org/10.1242/jcs.190835

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