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Clasp2 ensures mitotic fidelity and prevents differentiation of epidermal keratinocytes

Epidermal homeostasis is tightly controlled by a balancing act of self-renewal or terminal differentiation of proliferating basal keratinocytes. An increase in DNA content as a consequence of a mitotic block is a recognized mechanism underlying keratinocyte differentiation, but the molecular mechani...

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Detalles Bibliográficos
Autores principales: Shahbazi, Marta N., Peña-Jimenez, Daniel, Antonucci, Francesca, Drosten, Matthias, Perez-Moreno, Mirna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339885/
https://www.ncbi.nlm.nih.gov/pubmed/28069833
http://dx.doi.org/10.1242/jcs.194787