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Clasp2 ensures mitotic fidelity and prevents differentiation of epidermal keratinocytes
Epidermal homeostasis is tightly controlled by a balancing act of self-renewal or terminal differentiation of proliferating basal keratinocytes. An increase in DNA content as a consequence of a mitotic block is a recognized mechanism underlying keratinocyte differentiation, but the molecular mechani...
Autores principales: | Shahbazi, Marta N., Peña-Jimenez, Daniel, Antonucci, Francesca, Drosten, Matthias, Perez-Moreno, Mirna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339885/ https://www.ncbi.nlm.nih.gov/pubmed/28069833 http://dx.doi.org/10.1242/jcs.194787 |
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