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Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity

Epigenetic modifications alter transcriptional activity and contribute to the effects of environment on the individual risk of obesity and Type 2 Diabetes (T2D). Here, we have estimated the in vivo effect of a fat-enriched diet (HFD) on the expression and the epigenetic regulation of the Ankyrin rep...

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Detalles Bibliográficos
Autores principales: Raciti, Gregory A., Spinelli, Rosa, Desiderio, Antonella, Longo, Michele, Parrillo, Luca, Nigro, Cecilia, D’Esposito, Vittoria, Mirra, Paola, Fiory, Francesca, Pilone, Vincenzo, Forestieri, Pietro, Formisano, Pietro, Pastan, Ira, Miele, Claudia, Beguinot, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339897/
https://www.ncbi.nlm.nih.gov/pubmed/28266632
http://dx.doi.org/10.1038/srep43526