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Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity
Epigenetic modifications alter transcriptional activity and contribute to the effects of environment on the individual risk of obesity and Type 2 Diabetes (T2D). Here, we have estimated the in vivo effect of a fat-enriched diet (HFD) on the expression and the epigenetic regulation of the Ankyrin rep...
Autores principales: | Raciti, Gregory A., Spinelli, Rosa, Desiderio, Antonella, Longo, Michele, Parrillo, Luca, Nigro, Cecilia, D’Esposito, Vittoria, Mirra, Paola, Fiory, Francesca, Pilone, Vincenzo, Forestieri, Pietro, Formisano, Pietro, Pastan, Ira, Miele, Claudia, Beguinot, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339897/ https://www.ncbi.nlm.nih.gov/pubmed/28266632 http://dx.doi.org/10.1038/srep43526 |
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