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An engineered food-grade Lactococcus lactis strain for production and delivery of heat-labile enterotoxin B subunit to mucosal sites

BACKGROUND: Recent researches have been focusing on mucosal immune adjuvants, which play the key roles in mucosal immunization and have become the limitation for non-injected vaccine development. Escherichia coli heat-labile enterotoxin B subunit (LTB) was regarded as a promising mucosal adjuvant fo...

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Detalles Bibliográficos
Autores principales: Sun, Nan, Zhang, Rongguang, Duan, Guangcai, Peng, Xiaoyan, Wang, Chen, Fan, Qingtang, Chen, Shuaiyin, Xi, Yuanlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339977/
https://www.ncbi.nlm.nih.gov/pubmed/28264682
http://dx.doi.org/10.1186/s12896-017-0345-6