Cargando…

Sclerostin's role in bone's adaptive response to mechanical loading

Mechanical loading is the primary functional determinant of bone mass and architecture, and osteocytes play a key role in translating mechanical signals into (re)modelling responses. Although the precise mechanisms remain unclear, Wnt signalling pathway components, and the anti-osteogenic canonical...

Descripción completa

Detalles Bibliográficos
Autores principales: Galea, Gabriel L, Lanyon, Lance E, Price, Joanna S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340132/
https://www.ncbi.nlm.nih.gov/pubmed/27742499
http://dx.doi.org/10.1016/j.bone.2016.10.008