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Two Distinct Actin Networks Mediate Traction Oscillations to Confer Focal Adhesion Mechanosensing

Focal adhesions (FAs) are integrin-based transmembrane assemblies that connect a cell to its extracellular matrix (ECM). They are mechanosensors through which cells exert actin cytoskeleton-mediated traction forces to sense the ECM stiffness. Interestingly, FAs themselves are dynamic structures that...

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Detalles Bibliográficos
Autores principales: Wu, Zhanghan, Plotnikov, Sergey V., Moalim, Abdiwahab Y., Waterman, Clare M., Liu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340160/
https://www.ncbi.nlm.nih.gov/pubmed/28256237
http://dx.doi.org/10.1016/j.bpj.2016.12.035