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Two Distinct Actin Networks Mediate Traction Oscillations to Confer Focal Adhesion Mechanosensing
Focal adhesions (FAs) are integrin-based transmembrane assemblies that connect a cell to its extracellular matrix (ECM). They are mechanosensors through which cells exert actin cytoskeleton-mediated traction forces to sense the ECM stiffness. Interestingly, FAs themselves are dynamic structures that...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340160/ https://www.ncbi.nlm.nih.gov/pubmed/28256237 http://dx.doi.org/10.1016/j.bpj.2016.12.035 |