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AXL modulates extracellular matrix protein expression and is essential for invasion and metastasis in endometrial cancer

The receptor tyrosine kinase AXL promotes migration, invasion, and metastasis. Here, we evaluated the role of AXL in endometrial cancer. High immunohistochemical expression of AXL was found in 76% (63/83) of advanced-stage, and 77% (82/107) of high-grade specimens and correlated with worse survival...

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Detalles Bibliográficos
Autores principales: Divine, Laura M., Nguyen, Mai R., Meller, Eric, Desai, Riva A., Arif, Batool, Rankin, Erinn B., Bligard, Katherine H., Meyerson, Cherise, Hagemann, Ian S., Massad, Maria, Thaker, Premal H., Hagemann, Andrea R., McCourt, Carolyn K., Powell, Matt A., Mutch, David G., Fuh, Katherine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340229/
https://www.ncbi.nlm.nih.gov/pubmed/27764792
http://dx.doi.org/10.18632/oncotarget.12637