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Detecting High-Order Epistasis in Nonlinear Genotype-Phenotype Maps
High-order epistasis has been observed in many genotype-phenotype maps. These multi-way interactions between mutations may be useful for dissecting complex traits and could have profound implications for evolution. Alternatively, they could be a statistical artifact. High-order epistasis models assu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340324/ https://www.ncbi.nlm.nih.gov/pubmed/28100592 http://dx.doi.org/10.1534/genetics.116.195214 |